PAM是測(cè)量機(jī)械痛閾的新型工具,是專為關(guān)節(jié)炎研究設(shè)計(jì)的,特別適合用于嚙齒類動(dòng)物膝或足踝關(guān)節(jié)的疼痛評(píng)估;此外,配備一個(gè)爪壓力傳感器后,該儀器也可用于大小鼠爪的痛覺(jué)研究。
PAM是測(cè)量機(jī)械痛閾的新型工具,是專為關(guān)節(jié)炎研究設(shè)計(jì)的,特別適合用于嚙齒類動(dòng)物膝或足踝關(guān)節(jié)的疼痛評(píng)估;此外,配備一個(gè)爪壓力傳感器后,該儀器也可用于大小鼠爪的痛覺(jué)研究。
分辨率:0.1g
最大適用力:1500g
凈重:1.4Kg
毛重:2.7Kg
包裝規(guī)格:46x38x27cm
特征 |
優(yōu)點(diǎn) |
力直接作用于關(guān)節(jié) |
直接測(cè)量誘發(fā)疼痛 |
專為關(guān)節(jié)炎研究設(shè)計(jì) |
傳感器著力點(diǎn)外形根據(jù)嚙齒類動(dòng)物關(guān)節(jié)制造 |
可選配爪壓力傳感器 |
PAM 也可作為一臺(tái)手持的壓痛儀使用 |
● Method Paper: N. J. Barton et al.: “A novel behavioural technique for measuring hypersensitivity in a rat model of joint pain”. J. Neurosc. Methods,163, 67–75, 2007.
● J. Leuchtweis et al.: “Validation of the Digital Pressure Application Measurement (PAM) Device for Detection of Primary Mechanical Hyperalgesia in Rat and Mouse Antigen-Induced Knee Joint Arthritis...” Methods & Findings in Exp. & Clinical Pharmacol., 32(8): 581-589, 2010
● T. Schwagarus et alia: “A New Method for Measuring CFA-induced Mechanical Hyperalgesia in the Rat” Evotec 2012
● D. Amorim et alia: “Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis” Behav. Brain Res 265: 12-21, 2014
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●P. Di Giminiani et alia: “Nociceptive responses to thermal and mechanical stimulations in awake pigs” Eur. J. Pain 17(5): 638-648, 2013
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